Showing posts with label autism. Show all posts
Showing posts with label autism. Show all posts

Thursday, November 30, 2017

Christopher Exley has Become the New Face of the Anti-Vaxx Aluminium Grift

A new study by Mold et al. Aluminium in brain tissue in autism is not Exley's (corresponding author) first foray into aluminium as the cause of name-that-disorder by any stretch.  His publications vilify aluminium for a sundry of unrelated observations such as impaired sperm counts and quality, Alzheimer's Disease, "vaccine-induced" macrophagic myofaciitis and chronic fatigue syndrome along with fellow aluminium grifter Gherardi, breast cancer and of course vaccines.

The study Aluminium in brain tissue in autism is problematic from the start.  As Orac and The Blood-Brain Barrier Scientist note, Christopher Exley sits on the editorial board of the “Journal of Trace Elements in Medicine and Biology“ where the study was published.  The study also had an extremely rapid submission to acceptance time frame which was 26 October for submission, 21 November for a submitted revision, 23 November for acceptance and 26 November for online publication.  The sole funding source for this study was the Child Medical Safety Research Institute (CMSRI) which is a Dwoskin family foundation.  CMSRI is the funding source for the duo of Shaw and Tomljenovic to the tune of $900,000.00.  Clare Dwoskin is very very anti-vaccine which is evidenced by her statement to journalist John Stossel:
What his daughter went through is NOTHING compared to what the families of autistic children go through every day of their lives. No disease can match this record of human devastation. Vaccines are a holocaust of poison on our children’s brains and immune systems. Shame on you all.
More on what kind of "research" the Dwoskins finance can be found here and here.  The Dwoskins' latest study (prior to this one) with Christopher Shaw as the corresponding author was retracted due to image manipulation and dodgy methods.

While these issues individually don't disqualify the merits of a study, taken together they do cast serious doubt on the scientific rigour, review and impartiality of the study.  More importantly, the methods and results are the issues which ultimately render this study completely meaningless.

The thrust of this study is laid out in the abstract and introduction that state:
Human exposure to the environmental toxin aluminium has been linked, if tentatively, to autism spectrum disorder.
And
Paediatric vaccines that include an aluminium adjuvant are an indirect measure of infant exposure to aluminium and their burgeoning use has been directly correlated with increasing prevalence of ASD [11].
No it hasn't and is based upon some cherry-picked, weak studies.  The authors obtained five samples of brain tissue from people with confirmed autism spectrum disorder (ASD) for aluminium measurement.  They also obtained ten paraffin-embedded brain tissue samples from ASD individuals for fluorescent microscopy.

There were no controls.  Yes you read that correctly.  Not a single control for any aspect of this study; I'll elaborate.  The authors state:
Total aluminium was measured in each sample by transversely heated graphite furnace atomic absorption spectrometry (TH GFAAS) using matrix-matched standards and an established analytical programme alongside previously validated quality assurance data [13].
The "established analytical programme alongside previously validated quality assurance data" is their own protocol which is from these two studies, Brain burdens of aluminum, iron, and copper and their relationships with amyloid-β pathology in 60 human brains and The Identification of Aluminum in Human Brain Tissue Using Lumogallion and Fluorescence Microscopy.  I don't think validation means what they think it means.  This was internally-validated and not a recognised method for TH GFAAS by having been actually validated independently.

In the recent study two technical things (among many) stand out for the recently published "Aluminium in brain tissue in autism", first there was no mention of blanks used.  Granted it was an abbreviated description given the protracted version was explained in "Brain burdens of aluminum, iron and copper and their relationships with amyloid-β pathology in 60 human brains" (House, Exley et al. 2012), however there is no mention of an aluminium blank used to correct for contamination in either the body of the text nor in the description of Table 1 (Mold, Exley et al. 2017) where the values for aluminium content appear.  But this does appear in the cited study in both the body of the text and the description for it's Table 3 (House, Exley et al. 2012) aluminium content of brain samples.  It's worth mentioning that in the cited study (House, Exley et al. 2012), several samples have negative values and a high degree of intra-sample variation.  This is a problem with with their validation and they weakened this further by not including blanks in the autism study (Mold, Exley et al. 2017) as evidenced by the higher degree of intra-sample variation.

The second technical issue was the use of mean in the aluminium autism study.  Exley stated in his own cited brain aluminium study that due to non-normal distribution of intra-sample values, median with standard deviation was calculated.  This is correct but this was not done for the autism aluminium study, instead they used mean with standard deviation which skewed the means much higher because the outlier values were captured.  These values are further meaningless since the standard deviations are higher than the mean values for 3 of the four lobes sampled.
The mean (SD) aluminium content across all 5 individuals for each lobe were 3.82(5.42), 2.30(2.00), 2.79(4.05) and 3.82(5.17) μg/g dry wt. for the occipital, frontal, temporal and parietal lobes respectively.
Another huge problem for this study is both lack of controls and their own scale of pathology:
Previous measurements of brain aluminium, including our 60 brain study [15], have allowed us to define loose categories of brain aluminium content beginning with ≤1.00 μg/g dry wt. as pathologically benign (as opposed to ‘normal’). Approximately 40% of tissues (24/59) had an aluminium content considered as pathologically-concerning (≥2.00 μg/g dry wt.) while approximately 67% of these tissues had an aluminium content considered as pathologically- significant (≥3.00 μg/g dry wt.). The brains of all 5 individuals had at least one tissue with a pathologically-significant content of aluminium.
They cited The Identification of Aluminum in Human Brain Tissue Using Lumogallion and Fluorescence Microscopy (Mirza, Exley 2016) but it was not developed from samples of 60 brains; it was developed from multiple samples of one brain.  They rated the wildly variable observed aluminium levels in the Mold, Exley et al. 2017 study using a scale they developed in Mirza, Exley 2016 based on one single brain donation.  The authors must have a lot of contempt for their target audience and benefactors or are woefully inept to try and pass this stratification off as valid.  But more importantly, the results are meaningless because they did not include any controls, nor did they include any information on medical and dietary history nor causes of deaths of the individuals whose samples were donated.

The microscopy isn't any better.  There is no validation of the stain specificity nor control for contamination.  The Blood-Brain Barrier Scientist discusses the problems with the microscopy in detail.  Futhermore, they use Photoshop for visualising and enhancing images:
The subsequent merging of fluorescence and bright-field channels was achieved using Photoshop (Adobe Systems Inc. US).
This is not standard practice, in fact it's rather amateurish.  There are dedicated software packages available for fluorescent microscopes that track image capture and enhancements.  There is also no randomisation of microscopy sections nor blinding of the reader.  Presumably (or should be) there are several images taken and randomly selected for results discussion.  This was not done so for all we know, images are cherry-picked for maximum effect.  The fact that the microscopy suddenly had ten different samples (instead of the five previously noted) begs the question of IRB approval not to mention their Table S1 does not appear in the published study.

They make very far-reaching conclusions about their findings but fail to qualify any clinical relevance.  No histology was done so actual pathology of tissues samples is lacking.  The discussion is loaded with supposition with no evidence to support their claims.
A limitation of our study is the small number of cases that were available to study and the limited availability of tissue. Regarding the latter, having access to only 1g of frozen tissue and just 3 serial sections of fixed tissue per lobe would normally be perceived as a significant limitation. Certainly if we had not identified any significant deposits of aluminium in such a small (the average brain weighs between 1500 and 2000g) sample of brain tissue then such a finding would be equivocal. However, the fact that we found aluminium in every sample of brain tissue, frozen or fixed, does suggest very strongly that individuals with a diagnosis of ASD have extraordinarily high levels of aluminium in their brain tissue and that this aluminium is pre-eminently associated with non-neuronal cells including microglia and other inflammatory monocytes.
No the actual limitations of this study are the utter lack of controls, validation and rigour at every step of the way.  Non ASD people and with no pathology are going to also have aluminium deposits in their brain tissue.  Brain tissue banks are precious resources for neuroscience investigators.  It's a gross violation of the scientific method to be wasted on rubbish studies such as this to satisfy a rich matron with a hatred for vaccines.

ETA 12.18.17: Buzzfeed just reported that scientists they spoke with, who have relevant experience have rejected this study due to the problems with the methodology listed here and on other blogs.   Additionally, Christopher Exley has a substantial conflict of interest which he failed to report.  It turns out he is a benefactor and shill for SilicaWaters.com who sell ACILIS by Spritzer, a product that is touted by Exley to remove aluminium from our bodies.  SilicaWaters reports that 10% of their sales is donated to Exley's research into the benefits of drinking silica-rich water.



Sunday, April 17, 2016

Paging De Niro and Hightower...Wakefield isn't really in it to help autistics

Much ado has been made recently regarding the film Vaxxed: From Cover up to Catastrophe and rightfully so.  There have been numerous criticisms of the film and fortunately, Liz Ditz at I Speak of Dreams has been keeping a running list.  I won't be adding to that list any time soon, my interest is of a different sort.  Recently, it was revealed that Andrew Wakefield gave an email exchange he had with Grace Hightower, Robert De Niro's wife, to Celia Farber, a rabid HIV-AIDS denialist who serves as Wakefield's lackey to release personal communications that Wakefield apparently wants publicised.  Ms. Farber published an email exchange on her blog between Wakefield and Hightower but pulled it about an hour later.  It has been cached here (Hat tip: Mrs Pointer).

There are some revealing statements from Andrew Wakefield that warrant discussing.  First is this:
From: Andy Wakefield [email address redacted]
Date: Mon, Mar 28, 2016 at 2:55 PM
Subject: IMPORTANT
To: Grace DeNiro [email address redacted]

Did you share the confidential link to our movie with third parties? If so, who were these third parties?

From: Office Of Grace Hightower
Date: Mon, Mar 28, 2016 at 4:45 PM
Subject: Re: IMPORTANT
To: Andy Wakefield

Bob shared it with Jane Rosenthal and she shared it with her sister Pam Rawlings [sic]. These are the two people I am aware of his sharing it with. I shared it with no one.
This was two days after Wakefield's film was pulled from the Tribeca Film Festival. First, Jane Rosenthal is the co-founder, along with Robert DeNiro, of the Tribeca Film Festival and also co-chair.  She has an extensive and impressive portfolio of films she has produced, many featuring Robert De Niro.  Pam Rollins (not Rawlings) is Jane Rosenthal's sister and an associate professor at the University of Texas and an expert in communication and autism spectrum disorders.  Then:
On Mar 29, 2016, at 9:18 AM, Andy Wakefield wrote:
Grace, whatever may have happened – and I guess I will never know – in truth my heart goes out to you and Bob. Not only has your family’s life been blighted by autism, but you have experienced some of the relentless and ruthless pressure that has been my life for as long as I can remember.
In truth and healing
Andy

Andy Wakefield
Director
Autism Media Channel
Emphasis added.  Let that sink in.

Andrew Jeremy Wakefield essentially called Mr. De Niro's and Ms. Hightower's son a blight on their family.  Of course the devoted flock of Wakefield would argue that he only meant that autism was a blight but it's not.  Autism is part of who the person is for better or worse, just ask an autistic person.  This is the danger of embarking upon the "autism is a tragedy" train; parents no longer see their autistic child but rather one that has been "stolen by" autism" or has had "the soul taken away from them".  Bob Wright, founder of Autism Speaks testified at a 2007 congressional meeting about federal funding for autism.  Here is a chilling quote from him:
Our grandson, Christian, was diagnosed with autism in 2004.  Helpless, we watched him slip away into the cruel embrace of this disorder.  My wife, Suzanne, likens it to a kidnapping, as if someone had taken away the life Christian was meant to live. We all want nothing more than to have him back where he belongs, restored to his family--he's a little prisoner.
This is from the man who founded, what is perhaps, the largest autism charity in the country.  And from Bradley Whitford, the then-acting president of Autism Speaks (from the same meeting):
As my friend, John, has said many times, it's as if 1 in 150 American children was being kidnapped.  What would this Congress do if that was the case? What must it do to deal with these sad facts as they truly are?...

Portia has written a book about Dov called Strange Son.  Here's how she describes the kidnapping, ``It was his mind they came for.  They came to steal his mind. Before anyone gave it a name, even before I knew what it was, I knew it was in our house.  They were very, very dark things, and there was no way to get rid of them.  When I closed my eyes, I felt their shadows passing over me.  I didn't like to think about where they came from, or where they were going.  It was too frightening.  Dov was only a baby, and something was trying to steal him away.  I knew that that was what they did whenever I accidentally fell asleep.  Night after night, I sat beside his crib.  I knew he was slipping away from us, away from our world, and there was nothing I could do to stop it from happening, and there was nothing anybody could do, they told me.  So, I did the only things I could--I guarded him.  Although I knew it would do no good, because I could not guard his mind.  Then, one day, it happened. He was gone.  ''It is even more than just a tragedy for these kids, many of whom, like Dov, we now know to be of extraordinary intelligence, but trapped in bodies which do not allow them to effectively communicate or interact with the rest of us.  It's also a tragedy for our families and for our country.

As if it wasn't obvious, all people mentioned subscribe to the vaccine-causation idea of autism.  Incidentally, De Niro and Hightower are supporters of Autism Speaks. They don't accept their child has been born that way and autism isn't something done to him by vaccines.  That is what is so vile about Andrew Wakefield's statement.  More on that later.  Ms. Hightower not only doesn't appear to be bothered by such a remark but feels sorry for Wakefield:
On Mar 30, 2016, at 3:42 PM, Office of Grace Hightower wrote:

Andy,
Will you give me a call. I have an idea.
I feel awful about what happened and how it happened. I found out that the film was pulled along with the rest of the world.
Grace
The exchange continues:
On Mar 31, 2016, at 5:06 PM, Andy Wakefield wrote:

I will. I am headed for LAX and will try from there.
Andy
Sent from my iPhone

On Fri, Apr 1, 2016 at 9:39 AM, Office of Grace Hightower wrote:

Andy,
Just saw Ian Lipkin’s write up in NYT on March 30th you are entitled to a rebuttal. Also he was one of two doctors that I found out consulted TriBeCa. The other is Pam Rollins of Dallas, Jane Rosenthal’s sister. Don’t know of any others but, will let you know if I hear of any others. I spoke with Ian and found him to be quite pro industry and not at all really interested in autism.
Best,

Grace
"Not at all really interested in autism"?  Let's see, Dr. Lipkin is only the principle investigator for the Autism Birth Cohort Project.  What are Andrew Wakefield's credentials again?  The exchange concludes with this:
On Apr 1, 2016, at 11:30 AM, Andy Wakefield wrote:

In flight. It seems to me that Rosenthal’s breach of confidentiality is a dismissible offense. We were assured there would be no consequence to her breach and clearly there was – one that amounts to defamation. We arrive around 12.00 in NYC. I will call and perhaps we could grab a coffee over the weekend.
Andy
From: Business Office 1

Date: Fri, Apr 1, 2016 at 5:34 PM

Subject: Re: Reflections
To: Andy Wakefield
Yes, I recalled. I am in Florida now will be in NYC afternoon of April 4th.
Are you still in town? Would like to see and chat.

Sent from my iPhone
On one hand Wakefield suggests to Ms. Hightower that Jane Rosenthal should be removed from chairing the Tribeca Film Festival for "breach of confidentiality" yet has absolutely no problem handing a confidential email exchange to Celia Farber to publish.  This isn't the first time he's done this.  Wakefield's sheer arrogance is astonishing.  It will be interesting to see what transpires after this.  But this is only a part of the problem.

What is so very disturbing about this exchange is Wakefield's contempt for autistics while at the same time claiming to champion them.  Admittedly, I haven't seen the movie but will, although all I need to know is in the trailer.  Wakefield and company portray autistics in the worst possible light while portraying the parents as victims.

I have to ask, did anyone get informed consent from the autistic children in the film?  Did they get a say in whether they would like to be portrayed as damaged blights to their families and society?  I think we all know the answer to that.  Sadly, that is the power of Wakefield, his hustle to make himself attractive to otherwise (in some cases) intelligent people.  He appeals to the parents greatest fears and vulnerabilities.  He perpetuates the notion that autistics are less than human and exploits them for his own gain.  This is a very prevalent theme amongst the vaccines-causes-autism crowd.

Wakefield's co-producer Polly Tommey (founder of Autism Media Channel which Wakefield is the director of but isn't listed) allowed her son Billy to be exploited in this film.  Polly Tommey's daughter Bella is also in it and has a blog.  Bella wrote a post in October 2014 which was a dehumanising exposé of her own brother thinly-veiled as a special plea for her own martyrdom.  I posted a comment on the blog but it was removed:

Raising autistic children is a challenge; having an autistic sibling is a challenge but one crucial detail that is left out of this for vaccine-causation parents is that their children have the right to privacy; they have the right to dignity; they have a right to be raised in an environment which does not make them believe they are damaged.  This is the slippery-slope that ensues when parents view autism as a tragedy, something external foisted upon their children who would have been perfect otherwise.  They become less-than-human.

Lesile Weghorn of The Scientific Parent recently wrote a compelling article about how autistics feel about themselves when referred to as "vaccine-damaged".  It is gut-wrenching that autistics have to grow up in a world where they are thought of as a tragedy, a burden and now, a blight on their families.  Did Robert DeNiro and Grace Hightower even bother to talk to some autistics, perhaps even their own son about how autistics are portrayed in the media?  Perhaps they would like to talk to real autism advocates, other parent/advocates of autistic children and autistics about how they feel and how damaging Wakefield's film is, not only on a public health basis but how cruelly he depicts autistics.

Andrew Wakefield is a professional parasite who slimed his way into the De Niro's hearts preying upon their vulnerability, desperation and celebrity.  I wonder though, even if Robert De Niro and Grace Hightower subscribe to the vaccine-causation idea, would they consent to have their son portrayed in the manner Wakefield exploited in his film?  Even more importantly, would their son consent to be portrayed in such a humiliating manner?  If they don't have a problem with their son being called a blight on their family would they mind their son's personal details on display for public consumption?  If they would have a problem with that then perhaps they should reconsider Andrew Wakefield as an ally and take a critical look at who he really is because he isn't an autism advocate or researcher or even film-maker as he so recently fancies himself. 

De Niro and Hightower have the ability and resources to make a real difference and a positive impact on issues surrounding autism.  Pimping a fraud of a documentary about an issue that has been settled is intellectually and socially lazy.  Giving a platform to an unethical, disgraceful excuse for a physician who has damaged public health and profoundly contributed to the negative perception of autistics is an affront to all autistics and their families.

Friday, April 1, 2016

TMI - too much information - join National Autistic Society's new campaign

A young child in purple shirt, surrounded by many people and sounds, holds their ears shut to block out the sensory input - white on pink letters spell "TOO MUCH INFORMATION"

The British National Autistic Society (NAS) has launched a new campaign today, on 1 April, the start of Autism "Awareness" Month. Shockingly, there is very little awareness or acceptance of autistic children and adults in the UK:

28% of autistic people have been asked to leave a public space because of behaviour associated with their autism, 79% of autistic people and 70% of parents felt socially isolated.
The NAS argues that if someone sees only a "naughty kid" when they see a child in sensory overload, they clearly don't have enough information yet. They ask everyone: put yourself on the map and support the NAS to get everyone to understand autism.

A purple outline of the UK and Northern Ireland with bright dots representing clusters of supporters, on the left in white letters on pink background "PUT YOURSELF ON THE MAP"

Visit their site and check out the NAS' material, including a movie illustrating the sensory overload for a young autistic boy. This morning, on the BBC, he explained he hoped:

"this [movie] would cause awareness and respect, because that's as important as anything"

Tuesday, April 29, 2014

The FDA Takes Action Against Quack Autism "Cure" Peddlers

The FDA announced on Friday 25 April 2014 that they have issued warnings to "companies" who have been making false, misleading and dangerous claims regarding some of the more heinous "autism cures".
April is National Autism Awareness Month, a fitting time to think about the growing need for concern and awareness about autism.
One thing that is important to know up front: There is no cure for autism. So, products or treatments claiming to “cure” autism do not work as claimed. The same is true of many products claiming to “treat” autism. Some may carry significant health risks.
The Food and Drug Administration (FDA) plays an important role in warning these companies against making false or misleading claims.
Some of the "cures" that the FDA has warned about are:
  • “Chelation Therapies.” These products claim to cleanse the body of toxic chemicals and heavy metals by binding to them and “removing” them from circulation. They come in a number of forms, including sprays, suppositories, capsules, liquid drops and clay baths. FDA-approved chelating agents are approved for specific uses, such as the treatment of lead poisoning and iron overload, and are available by prescription only. FDA-approved prescription chelation therapy products should only be used under medical supervision. Chelating important minerals needed by the body can lead to serious and life-threatening outcomes.
Chelation has quite a fan base over at the autism-hating pit also known as Age of Autism. Unfortunately for their children who have been subjected to this dangerous "treatment", the need for chelation is based upon bogus tests that use a chelator administered to the child, urine collected and then "tested".  These provoked challenge tests are not recognised as valid by any regulatory authority any where in the world. 

Research suggests that chelating in the absence of heavy metals can actually cause permanent neurological damage in children because the chelators will scavenge essential nutrients necessary for growth and development.  None of those peddling chelation for autism have any safety or efficacy data to support their claims.  Jenny McCarthy's Generation Rescue peddles chelation along with off-label prescription drug use to "recover" your autistic child.
  • Hyperbaric Oxygen Therapy. This involves breathing oxygen in a pressurized chamber and has been cleared by FDA for certain medical uses, such as treating decompression sickness suffered by divers. It has not been cleared for autism, among other conditions.
TACA via autism crank Kenneth Stoller make very specific claims regarding Hyperbaric Oxygen Therapy (HBOT) and "treating" autism. Forcing special needs children into HBOT chambers is not only cruel but has already resulted in the death of at least one child and his grandmother for another unapproved use of HBOT.  There are no valid data to support HBOT as an effective autism treatment although that doesn't stop the quacks from taking advantage of desperate parents.
  • Miracle Mineral Solution. Also known as Miracle Mineral Supplement and MMS, this product becomes a potent chemical that‘s used as bleach when mixed according to package directions. FDA has received reports of consumers who say they experienced nausea, severe vomiting and life-threatening low blood pressure after drinking the MMS and citrus juice mixture.
This is perhaps one of the most horrifying and ludicrous autism "cures" and Kerri Rivera is at the forefront of this disgusting and abusive snake oil peddling.  Ms. Rivera has presented MMS/Chlorine Dioxide (CD) as an autism cure at the premier crankfest AutismOne since 2010 and will be there again this year claiming 128 children "recovered" by bleaching them. Ms. Rivera would have her followers believe that since chlorine dioxide isn't sodium hypochlorite (household bleach) that it isn't a bleach.  She is either too stupid, too evil or both to make this claim as "bleach" is a classification of chemical compounds, not a single one as Emily Willingham so aptly demonstrated.  

Users abusers of MMS/CD report nausea, vomiting, severe diarrhoea but Ms. Rivera blithely exclaims that "it's working".  Parents who force this on their autistic children also report and proudly supply pictures of their children's intestinal mucosa which is sloughing off to which Ms. Rivera claims that it's "parasites".  Ms. Rivera lives hides in Mexico but peddles her snake oil globally so is not immune from FDA action.
  • Detoxifying Clay Baths. Added to bath water, these products claim to draw out chemical toxins, pollutants and heavy metals from the body, falsely offering “dramatic improvement” for autism symptoms.
A completely useless and potentially dangerous "autism treatment".  Clay baths are not regulated and can contain harmful contaminants, the very things that peddlers claim they are purging from the body.
  • CocoKefir probiotics products. Product claims include being a “major key” to recovery from autism, but they are not proven safe and effective for this advertised use.
CocoKefir is a sponsor of AutismOne this year and although they have received at least one FDA warning letter, are still making claims that their products treat autism. Again, these products are considered supplements and are not regulated so may contain contaminants and other ingredients which are not listed.

I applaud this action by the FDA as special needs children are being subjected to dangerous, harmful and downright abusive "treatments" by dubious quacks and cranks.  Now if only the AMA and AAP will recognise these abusive "treatments" for what they are and disciplining their own physicians, perhaps autistic children may be spared from harms perpetrated by the very people who should be protecting them.

Friday, March 7, 2014

75 studies that show no link between vaccines and autism UPDATED to 107

Edited to fix links and to add more studies for a new total of 107 on 11 March 2014

Guest blog, compiled by Allison Hagood, Luci Baldwin, Kathy McGrath and Nathan Boonstra and originally published on the "Your Baby's Best Shot" Facebook page. I am grateful for the permission to repost!

If anyone still tries to pull the "vaccines cause autism" card on you, provide them with a link to this note!

Albizzati, A., Moré, L., Di Candia, D., Saccani, M., Lenti, C.  Normal concentrations of heavy metals in autistic spectrum disorders.  Minerva Pediatrica.  2012. Feb;64(1):27-31 http://www.ncbi.nlm.nih.gov/pubmed/22350041

Afzal, MA., Ozoemena, LC., O’Hare, A., Kidger, KA., Bentley, ML., Minor, PD. Absence of detectable measles virus genome sequence in blood of autistic children who have had their MMR vaccination during the routine childhood immunization schedule of UK.   Journal Medical Virology.  2006 May;78(5):623-30.  http://www.ncbi.nlm.nih.gov/pubmed/16555271

Ahearn WH. What Every Behavior Analyst Should Know About the "MMR Causes Autism" HypothesisArchive of Behavior Analysis in Practice.  2010.   Spring;3(1):46-50. http://www.ncbi.nlm.nih.gov/pubmed/22479671

Allan, GM., Ivers, N.  The autism-vaccine story: fiction and deception?  Canadian Family Physician.  Oct 2010; 56(10): 1013. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954080/

Andrews, N., Miller, E., Grant, A., Stowe, J., Osborn, V., & Taylor, B. (2004).  Thimerosal exposure in infants and developmental disorders: a retrospective cohort study in the United Kingdom does not support a causal association.  Pediatrics, 114, 584-591. http://www.ncbi.nlm.nih.gov/pubmed/15342825 

Andrews, N., Miller, E., Taylor, B., Lingam, R., Simmons, A., Stowe, J., Waight, P.  Recall bias, MMR and autism.  Archives of Disease in Childhood.  Dec 2002; 87(6): 493–494.  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1755823/pdf/v087p00493.pdf

Baird, G., Pickles, A., Simonoff, E., Charman, T., Sullivan, P., Chandler, S., Loucas, T., Meldrum, D., Afzal, M., Thomas, B., Jin, L., Brown, D.  Measles vaccination and antibody response in autism spectrum disorders.  Archives of Disease in Childhood.  2008 Oct;93(10):832-7. doi: 10.1136/adc.2007.122937. Epub 2008 Feb 5.  http://www.ncbi.nlm.nih.gov/pubmed/18252754

Berger, BE., Navar-Boggan, AM., Omer, SB.  Congenital rubella syndrome and autism spectrum disorder prevented by rubella vaccination--United States, 2001-2010.   BMC Public Health.  2011 May 19;11:340. doi: 10.1186/1471-2458-11-340. http://www.ncbi.nlm.nih.gov/pubmed/21592401

Black, C., Kaye, JA.  Relation of childhood gastrointestinal disorders to autism:  nested case-control study using data from the UK General Practice Research Database.  British Medical Journal.  2002; 325(7361):419-21.  http://dx.doi.org/10.1136/bmj.325.7361.419

Bower, H.  New research demolishes link between MMR vaccine and autism.  British Medical Journal.  1999.  Jun 19;318(7199):1643. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1116011/

Chen, W., Landau, S., Sham, P., & Fombonne, E. (2004).  No evidence for links between autism, MMR and measles virus.  Psychological Medicine, 34(3), 543-553. http://www.ncbi.nlm.nih.gov/pubmed/15259839

Christie, B.  Scottish expert group finds no link between MMR and autism.  British Medical Journal,  2002. May 11;324(7346):1118. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1172158/

Clements, CJ., McIntyre, PB.  When science is not enough – a risk/benefit profile of thiomersal-containing vaccines.   Expert Drug Opinion Safety.  2006. Jan;5(1):17-29. http://www.ncbi.nlm.nih.gov/pubmed/16370953    

Dales, L., Hammer, S. J., & Smith, N. J. (2001). Time trends in autism and in MMR immunization coverage in California.   JAMA, 285(9), 1183-1185. http://www.ncbi.nlm.nih.gov/pubmed/11231748

De Los Reyes, EC.  Autism and immunizations: separating fact from fiction.  JAMA Neurology.   2010;67(4):490-492. doi:10.1001/archneurol.2010.57. http://archneur.jamanetwork.com/article.aspx?articleid=799645

DeWilde, S., Carey, IM., Richards, N., Hilton, SR., Cook, DG.  Do children who become autistic consult more often after MMR vaccination?  British Journal of General Practice.  2001 Mar;51(464):226-7.  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1313956/

Demicheli, V., Jefferson, T., Rivetti, A., & Price, D. (2005).  Vaccines for measles, mumps and rubella in children. Cochrane Database Syst Rev, 4. (a review of 31 studies) http://www.ncbi.nlm.nih.gov/pubmed/22336803

DeStefano, F.  MMR vaccine and autism: a review of the evidence for a causal association.   Molecular Psychiatry.  2002;7 Suppl 2:S51-2.http://www.ncbi.nlm.nih.gov/pubmed/12142951

DeStefano, F., Chen, RT.  Autism and measles, mumps, and rubella vaccine: No epidemiological evidence for a causal association.  The Journal of Pediatrics.  2000 Jan;136(1):125.  http://www.ncbi.nlm.nih.gov/pubmed/10681219    

DeStefano, F., Bhasin, T. K., Thompson, W. W., Yeargin-Allsopp, M., & Boyle, C. (2004).  Age at first measles-mumps-rubella vaccination in children with autism and school-matched control subjects: a population-based study in metropolitan AtlantaPediatrics, 113(2), 259-266. http://www.ncbi.nlm.nih.gov/pubmed/14754936

DeStefano F., Price CS., Weintraub, ES.  Increasing exposure to antibody-stimulating proteins and polysaccharides in vaccines is not associated with risk of autism.   Journal of Pediatrics.  2013 Aug;163(2):561-7. doi: 10.1016/j.jpeds.2013.02.001. Epub 2013 Mar 30. http://www.ncbi.nlm.nih.gov/pubmed/23545349

DeStefano F., Thompson, WW.  MMR vaccine and autism: an update of the scientific evidence. Expert Rev Vaccines. 2004 Feb;3(1):19-22.  http://www.ncbi.nlm.nih.gov/pubmed/14761240

DeStefano F., Thompson, WW.  MMR vaccination and autism: is there a link?  Expert Opinion on Drug Safety.  2002 Jul;1(2):115-20.  http://www.ncbi.nlm.nih.gov/pubmed/12904145

DeStefano, F.  Chen, RT.  Negative association between MMR and autism.  Lancet. 1999 Jun 12;353(9169):1987-8.  http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(99)00160-9/fulltext

DeStefano, F., Chen, RT.  Autism and measles-mumps-rubella vaccination:  controversy laid to rest?  CNS Drugs.  2001. 2001;15(11):831-7.  http://www.ncbi.nlm.nih.gov/pubmed/11700148

D’Souza J., Todd T.  Measles-mumps-rubella vaccine and the development of autism or inflammatory bowel disease: the controversy should end.  Journal of Pedatric Pharmacology and Therapeutics.   2003 Jul;8(3):187-99. doi: 10.5863/1551-6776-8.3.187. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469143/

D’Souza, Y., Fombonne, E., Ward, BJ.  No evidence of persisting measles virus in peripheral blood mononuclear cells from children with autism spectrum disorder.  Pediatrics.  2006 Oct;118(4):1664-75.  http://www.ncbi.nlm.nih.gov/pubmed/17015560

Doja, A., & Roberts, W. (2006).  Immunizations and autism: A review of the literature.  The Canadian Journal of Neurological Sciences, 33(4), 341-346. http://www.ncbi.nlm.nih.gov/pubmed/17168158

Elliman, D., Bedford, H.   MMR: where are we now?  Archives of Disease in Childhood.   2007 Dec;92(12):1055-7. Epub 2007 Jul 11.  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2066086/ 

Farrington, C., Miller, E., & Taylor, B. (2001).  MMR and autism: further evidence against a causal association.  Vaccine, 19(27), 3632-3635. http://www.ncbi.nlm.nih.gov/pubmed/11395196

Fitzpatrick, M.  The end of the road for the campaign against MMR.  British Journal of General Practice.  2007 Aug;57(541):679.  http://www.ncbi.nlm.nih.gov/pubmed/17688775

Fombonne, E., & Chakrabarti, S. (2001).  No evidence for a new variant of measles-mumps-rubella–induced autism.  Pediatrics, 108(4), e58-e58. http://www.ncbi.nlm.nih.gov/pubmed/11581466

Fombonne, E., Zakarian, R., Bennett, A., Meng, L., & McLean-Heywood, D. (2006).  Pervasive developmental disorders in Montreal, Quebec, Canada: Prevalence and links with immunizations.  Pediatrics 118(1) e139-e150; doi:10.1542/peds.2005-2993. http://pediatrics.aappublications.org/content/118/1/e139

García-Fernández, L., Hernández, AV., Suárez Moreno, V., Fiestas, F.  Addressing the controversy regarding the association between thimerosal-containing vaccines and autism.  Revista Peruana de Medicine Experimental Salud Publica. 2013 Apr;30(2):268-74. http://www.ncbi.nlm.nih.gov/pubmed/23949514

Gentile, I., Bravaccio, C., Bonavolta, R., Zappulo, E., Scarica, S., Riccio, MP., Settimi, A., Portella, G., Pascotta, A., Borgia, G.  Response to measles-mumps-rubella vaccine in children with autism spectrum disordersIn Vivo 2013 May-Jun;27(3):377-82. http://www.ncbi.nlm.nih.gov/pubmed/23606694

Glasper, EA.  New evidence reaffirms the safety of the MMR vaccine.  British Journal of Nursing. 2002 Jun 27-Jul 10;11(12):794.  http://www.internurse.com/cgi-bin/go.pl/library/article.cgi?uid=10298;article=BJN_11_12_794_0

Halsey, NA., Hyman, SL.  Measles-mumps-rubella vaccine and autistic spectrum disorder: report from the New Challenges in Childhood Immunizations Conference convened in Oak Brook, Illinois.   June 12-13, 2000.   Pediatrics.  2001 May;107(5):E84.  http://www.ncbi.nlm.nih.gov/pubmed/11331734

Hayney MS.  Vaccine Safety:  no link between thimerosal and autismJournal of American Pharmacists Association.  2003. 2004 Nov-Dec;44(6):725-6. http://japha.org/article.aspx?articleid=1039011   

Hertz-Picciotto, I., Green, P., Delwiche, L., Hansen, R., Walker, C., & Pessah, I. (2010).  Blood mercury concentrations in CHARGE Study children with and without autism. Environmental Health Perspectives, 118(1), 161-166. doi:10.1289/ehp.0900736 http://www.ncbi.nlm.nih.gov/pubmed/20056569

Hensley, E. Briars, L.  Closer look at autism and the measles-mumps-rubella vaccineJournal of American Pharmacist’s Association.  2003.  2010 Nov-Dec;50(6):736-41. doi: 10.1331/JAPhA.2010.10004.  http://www.ncbi.nlm.nih.gov/pubmed/21071320 

Heron, J., Golding, J., ALSPAC Study Team.  Thimerosal exposure in infants and developmental disorders: a prospective cohort study in the United Kingdom does not support a causal association.  Pediatrics.  2004 Sep;114(3):577-83. http://www.ncbi.nlm.nih.gov/pubmed/15342824

Hessel, L.  Mercury in vaccines.  Bulletin of the National Academy of Medicine. 2003;187(8):1501-10.  http://www.ncbi.nlm.nih.gov/pubmed/15146581

Hiroshi, T., Suzumura, S., Shirakizawa, F., Wada, N., Tanaka-Taya, K., Arai, S., Okabe, N., Ichikawa, H., Sato, T.  An epidemiological study on Japanese Autism concerning Routine Childhood Immunization History.  Japanese Journal of Infectious Diseases.  56, 114-117, 2003. http://www0.nih.go.jp/JJID/56/114.pdf

Honda, H., Shimizu, Y., & Rutter, M. (2005).  No effect of MMR withdrawal on the incidence of autism: a total population study.  Journal of Child Psychology and Psychiatry.  46(6), doi: 10.1111/j.1469-7610.2005.01425.x.  http://www.ncbi.nlm.nih.gov/pubmed/15877763

Hornig, M., Briese, T., Bule, T., Bauman, M.L., Lauwers, G., Siemetzki, U., Hummel, K., Rota, PA., Bellini, WJ., O’Leary, JJ., Sheils, O., Alden, E., Pickering, L., Lipkin, W.I.  Lack of association between measles virus vaccine and autism with enteropathy: a case-control study.  2008.  PLoS One, 3(9), e3140. doi: 10.1371/journal.pone.0003140. http://www.ncbi.nlm.nih.gov/pubmed/18769550  

Hurley, A., Tadrous, M., Miller, ES.  Thimerosal-containing vaccines and autism: a review of recent epidemiological studies.  Journal of Pediatric Pharmacology and Therapeutics.  2010 Jul-Sep; 15(3): 173-181.  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018252/

Hviid A., Stellfeld, M., Wohlfahrt, J., Melbye, M.   Association between thimerosal-containing vaccine and autism - No causal relationship found.  JAMA. 2003 Oct 1;290(13):1763-6. http://www.ncbi.nlm.nih.gov/pubmed/14519711

Insitute  of Medicine (US) Immunization Safety Review Committee.  Immunization Safety Review:  Vaccines and Autisms.  Washington (DC): National Academies Press (US); 2004. http://www.ncbi.nlm.nih.gov/pubmed/20669467

Iqbal, S., Barile, JP., Thompson, WW., DeStefano, F.  Number of antigens in early childhood vaccines and neuropsychological outcomes at age 7–10years.  Pharmacoepidemiology and Drug Safety.  2013 Dec;22(12):1263-70. doi: 10.1002/pds.3482.  Epub 2013 Jul 12. http://www.ncbi.nlm.nih.gov/pubmed/23847024

Jefferson, T., Price, D., Demicheli, V., Bianco, E., European Research Program for Improved Safety Surveillance (EUSAFEVAC) Project.  Unintended events following immunization with MMR: a systematic review.  Vaccine.  2003 Sep 8;21(25-26):3954-60. http://www.ncbi.nlm.nih.gov/pubmed/12922131

Jick, H., Kaye, JA.  Epidemiology and possible causes of autism.  Pharmacotherapy. 2003 Dec;23(12):1524-30.  http://www.ncbi.nlm.nih.gov/pubmed/14695031

Kaye, J. A., del Mar Melero-Montes, M., & Jick, H.  Mumps, measles, and rubella vaccine and the incidence of autism recorded by general practitioners: a time trend analysis.  2001.  British Medical Journal, 322(7284), 460-463.  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1071423/

Klein, K. C., & Diehl, E. B.  Relationship between MMR vaccine and autism.   2004.  Annals of Pharmacotherapy, 38(7-8), 1297-1300.  http://www.ncbi.nlm.nih.gov/pubmed/15173555

Kuwaik, GA., Roberts, W., Zwaigenbaum, L., Bryson, S., Smith, IM., Szatmari, P., Modi, BM., Tanel, N., Brian, J.  Immunization uptake in younger siblings of children with autism spectrum disorder.  Autism.  2014 Feb;18(2):148-55. doi: 10.1177/1362361312459111. Epub 2012 Oct 8. http://www.ncbi.nlm.nih.gov/pubmed/23045216

Lazoff, T., Zhong, L., Piperni, T., Fombonne, E.  Prevalence of pervasive developmental disorders among children at the English Montreal School Board.  Canadian Journal of Psychiatry.  2010 Nov;55(11):715-20.  http://www.ncbi.nlm.nih.gov/pubmed/21070699

Lingam, R., Simmons, A., Andrews, N., Miller, E., Stowe, J., & Taylor, B. (2003).  Prevalence of autism and parentally reported triggers in a North-east London population.  Archives of Disease in Childhood, 88(8), 666-670.  http://www.ncbi.nlm.nih.gov/pubmed/12876158

Madsen, K.K., Hviid, A., Vestergaard, M., Schendel, D., Wohlfahrt, J., Thorsen, P., Olsen, J., Melbye, M.  A population-based study of measles, mumps, and rubella vaccination and autism.  2002.  The New England Journal of Medicine, 347(19), 1477-82.  http://www.ncbi.nlm.nih.gov/pubmed/12421889

Madsen KM., Hviid, A., Vestergaard, M., Schendel, D., Wohlfahrt, J., Thorsen, P., Olsen, J. Melbye, M.  MMR vaccination and autism--a population-based follow-up study.  Ugeskr Laeger.  2002.  Dec 2;164(49):5741-4.  http://www.ncbi.nlm.nih.gov/pubmed/12523209

Madsen, K.M., Lauritsen, M.B., Pedersen, C.B., Thorsen, P., Plesner, A.M., Andersen, P.H. & Mortensen, P.B.  Thimerosal and the occurrence of autism:  negative ecological evidence from Danish population-based data.  2003.  Pediatrics, 112, 604-606. doi: 10.1542/peds.112.3.204 http://www.ncbi.nlm.nih.gov/pubmed/12949291

Madsen, KM.  Vestergaard, M.   MMR and Autism:  what is the evidence for a causal association?  Drug Safety.  2004;27(12):831-40. http://www.ncbi.nlm.nih.gov/pubmed/15366972

Makela, A., Nuorti, J., & Peltola, H. (2002).  Neurologic disorders after measles-mumps-rubella vaccination.  Pediatrics, 110(5), 957-963.  http://www.ncbi.nlm.nih.gov/pubmed/12415036

Marin, M., Broder, KR., Temte, JL., Snider, DE., Seward, JF., (CDC).  Use of combination measles, mumps, rubella, and varicella vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP).  MMWR Recommendations and Reports.  2010 May 7;59(RR-3):1-12.  http://www.ncbi.nlm.nih.gov/pubmed/20448530

Marwick, C.  US Report finds no link between MMR and autism.  British Medical Journal.   May 5, 2001; 322(7294): 1083.  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1120232/

MacDonald, NE., Pickering, L. Canadian Paediatric Society, Infectious Diseases and Immunization Committee.  Autism Spectrum Disorder:  No causal relationship with vaccines.  Paediatric Child Health 2007;12(5):393-5.  http://www.cps.ca/documents/position/autistic-spectrum-disorder-no-causal-relationship-with-vaccines

Meadows, M.  IOM Report:  no link between vaccines and autism.  FDA Consumer. 2004 Sep-Oct;38(5):18-9.  http://www.ncbi.nlm.nih.gov/pubmed/15595144

Meilleur, AA., Fombonne, E.  Regression of language and non-language skills in pervasive development disorders.  Journal of Intellectual Disability Research.  2009 Feb;53(2):115-24. doi: 10.1111/j.1365-2788.2008.01134.x. Epub 2008 Nov 27. http://www.ncbi.nlm.nih.gov/pubmed/19054269

Miller, E.  Measles-mumps-rubella vaccine and the development of autism - epidemiologic evidence against such an association is compelling.  Seminars in Pediatric Infectious Diseases.  2003 Jul;14(3):199-206.  http://www.ncbi.nlm.nih.gov/pubmed/12913832

Miller, E., Andrews, N., Grant, A., Stowe, J., Taylor, B.  No evidence of an association between MMR vaccine and gait disturbance.  Archives of Disease in Childhood.  2005.  Mar;90(3):292-6. http://www.ncbi.nlm.nih.gov/pubmed/15723921

Miller, L., Reynolds J.  Autism and vaccination – the current evidenceJournals for Specialists in Pediatric Nursing.  2009 Jul;14(3):166-72. doi: 10.1111/j.1744-6155.2009.00194.x. http://www.ncbi.nlm.nih.gov/pubmed/19614825

Mrozek-Budzyn, D., Kiełtyka, A.  The relationship between MMR vaccination and the number of new cases of autism in children.  Przeglad epidemiologiczny.  2008;62(3):597-604. http://www.ncbi.nlm.nih.gov/pubmed/19108524

Mrozek-Budzyn, D., Kiełtyka, A.,  Majewska, R.  Lack of association between measles-mumps-rubella vaccination and autism in children:  a case-control study.  Pediatric Infectious Disease Journal.  2010 May;29(5):397-400. doi: 10.1097/INF.0b013e3181c40a8a. http://www.ncbi.nlm.nih.gov/pubmed/19952979

Mrozek-Budzyn, D., Majewska, R. Kiełtyka, A. & Augustyniak, M.  Lack of association between thimerosal-containing vaccines and autism.  Przeglad epidemiologiczny.  2011, 65(3), 491-495. http://www.ncbi.nlm.nih.gov/pubmed/22184954

Muhle, R., Trentacoste, SV., Rapin, I.  The genetics of autismPediatrics. 2004 May;113(5):e472-86.  http://www.ncbi.nlm.nih.gov/pubmed/15121991

Nelson, KB., Bauman, ML.  Thimerosal and autism?  Pediatrics.  2003.  Mar;111(3):674-9.http://pediatrics.aappublications.org/content/111/3/674.long

Offit, PA., Coffin, SE.  Communicating science to the public:  MMR vaccine and autism.  Vaccine.  2003.  Dec 8;22(1):1-6. http://www.ncbi.nlm.nih.gov/pubmed/14604564

Stratton, K., Ford, A., Rusch, E., Wright Clayton, E.  Committee to Review Adverse Effects of Vaccines; Institute of Medicine.  Adverse Effects of Vaccines: Evidence and Causality.  Washington, DC: The National Academies Press, 2012. (a review of more than ONE THOUSAND studies).  http://www.nap.edu/catalog.php?record_id=13164

Patja, A., Davidkin, I., Kurki, T.,  Marku, J., Kallio, T., Valle, M., Peltola, H.  Serious adverse events after measles-mumps-rubella vaccination during a fourteen-year prospective follow-up.  2000.  Pediatric Infectious Diseases Journal.  2000;19:1127-34.  http://www.nccn.net/~wwithin/MMR.pdf

Parker, S.K., Schwartz, B., Todd, J., Pickering, L.K.  Thimerosal-containing vaccines and autistic spectrum disorder: A critical review of published original data.  2004.  Pediatrics, 114, 793-804. http://www.ncbi.nlm.nih.gov/pubmed/15342856

Parker, S. Todd, J., Schwartz., B., Pickering, L.K.  Thimerosal-containing vaccines and autistic spectrum disorder: A critical review of published original data.  2005.  Pediatrics. Jan;115(1):200.  http://www.ncbi.nlm.nih.gov/pubmed/15630018

Pichichero, ME., Cernichiari, E., Lopreiato, J., Treanor, J.  Mercury concentrations and metabolism in infants receiving vaccines containing thiomersal: a descriptive study.  Lancet. 2002 Nov 30;360(9347):1737-41.  http://www.ncbi.nlm.nih.gov/pubmed/12480426

Peltola, H., Patja, A., Leinikki, P., Valle, M., Davidkin, I., & Paunio, M.  No evidence for measles, mumps, and rubella vaccine-associated inflammatory bowel disease or autism in a 14-year prospective study.  1998.  Lancet, 351(9112), 1327. http://www.ncbi.nlm.nih.gov/pubmed/9643797

Plotkin, S., Gerber, J. S., & Offit, P. A. (2009).  Vaccines and autism: a tale of shifting hypotheses.  Clinical Infectious Diseases, 48(4), 456-461. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908388/

Price, C. S., Thompson, W. W., Goodson, B., Weintraub, E. S., Croen, L. A., Hinrichsen, V. L., DeStefano, F.  Prenatal and infant exposure to thimerosal from vaccines and immunoglobulins and risk of autism.  2010.  Pediatrics, 126(4), 656-664. http://www.ncbi.nlm.nih.gov/pubmed/20837594

Roehr B.  Study finds no association between vaccines and autism.  2013.  British Medical Journal.  Apr 3;346:f2095. doi: 10.1136/bmj.f2095. http://www.ncbi.nlm.nih.gov/pubmed/23554072

Richler, J., Luyster, R., Risi, S., Hsu, W. L., Dawson, G., Bernier, R., ... & Lord, C. (2006). Is there a ‘regressive phenotype’ of Autism Spectrum Disorder associated with the measles-mumps-rubella vaccine?  A CPEA Study.  Journal of Autism and Developmental Disorders, 36(3), 299-316. http://www.ncbi.nlm.nih.gov/pubmed/16729252

Rumke, HC., Visser, HK.  Childhood vaccinations anno 2004. II. The real and presumed side effects of vaccination.  Nederlands Tijdschrift voor Geneeskunde.  2004 Feb 21;148(8):364-71. http://www.ncbi.nlm.nih.gov/pubmed/15032089  

Schechter, R., Grether, JK.  Continuing increases in autism reported to California's developmental services system: mercury in retrograde.  Archives of General Psychiatry.  2008 Jan;65(1):19-24. doi: 10.1001/archgenpsychiatry.2007.1. http://www.ncbi.nlm.nih.gov/pubmed/18180424

Schultz, ST.  Does thimerosal or other mercury exposure increase the risk for autism?  A review of the current literature.  Acta Neurobiologiae Experimentalis. 2010;70(2):187-95. http://www.ncbi.nlm.nih.gov/pubmed/20628442

Shevell, M.,Fombonne, E. Autism and MMR vaccination or thimerosal exposure: an urban legend?  Canadian Journal of Neurological Sciences.  2006 Nov;33(4):339-40. http://cjns.metapress.com/content/xqxx6ha3ufaeuunv/?genre=article&issn=0317-1671&volume=33&issue=4&spage=339

Smeeth, L., Cook, C., Fombonne, E., Heavey, L., Rodrigues, L. C., Smith, P. G., & Hall, A. J. (2004). MMR vaccination and pervasive developmental disorders: a case-control study.  The Lancet, 364(9438), 963-969. http://www.ncbi.nlm.nih.gov/pubmed/15364187

Smith, M. J., & Woods, C. R.  On-time vaccine receipt in the first year does not adversely affect neuropsychological outcomes.  Pediatrics.  2010. 125(6), 1134-1141. http://www.ncbi.nlm.nih.gov/pubmed/20498176

Solt, I., Bornstein, J.  Childhood vaccines and autism – much ado about nothing?  Harefuah. 2010 Apr;149(4):251-5, 260.  http://www.ncbi.nlm.nih.gov/pubmed/20812501

Singh, VK. Rivas, WH.  Detection of antinuclear and antilaminin antibodies in autistic children who received thimerosal-containing vaccines  - mercury as in thimerosal-containing vaccines is likely not related to autoimmune phenomenon in autism.   Journal of Biomedical Science.  2004 Sep-Oct;11(5):607-10.  http://www.ncbi.nlm.nih.gov/pubmed/15316135   

Steffenburg, S., Steffenburg, U., Gillberg, C.  Autism spectrum disorders in children with active epilepsy and learning disability:  comorbidity, pre and perinatal backgound, and seizure characteristics.   Developmental Medicine and Child Neurology.  2003 Nov;45(11):724-30. http://www.ncbi.nlm.nih.gov/pubmed/14580127   

Stehr-Green, P., Tull, P., Stellfeld, M., Mortenson, PB., Simpson, D.  Autism and thimerosal-containing vaccines: lack of consistent evidence for an association.   American Journal of Preventive Medicine.  2003 Aug;25(2):101-6.  http://www.ncbi.nlm.nih.gov/pubmed/12880876

Taylor, B.  Vaccines and the changing epidemiology of autism.  Child: Care, Health and Development Journal.  2006 Sep;32(5):511-9.  http://www.ncbi.nlm.nih.gov/pubmed/16919130

Taylor, B., Miller, E., Farrington, C., Petropoulos, M., Favot-Mayaud, I., Li, J., & Waight, P. A. (1999).  Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal association.  Lancet, 353(9169), 2026-20. http://www.ncbi.nlm.nih.gov/pubmed/10376617

Taylor, B., Miller, E., Lingam, R., Andrews, N., Simmons, A., & Stowe, J.  Measles, mumps, and rubella vaccination and bowel problems or developmental regression in children with autism: population study.  2002.  British Medical Journal, 324(7334), 393-396. http://www.ncbi.nlm.nih.gov/pubmed/11850369

Taylor, B., Lingam, R., Simmons, A., Stowe, J., Miller, E., Andrews, N.  Autism and MMR vaccination in North London: no causal relationship.   2002.  Molecular Psychiatry.                   7 Suppl2:S7-8.  http://www.ncbi.nlm.nih.gov/pubmed/12142932

Thjodleifsson, B., Davidsdóttir, K., Agnarsson, U., Sigthórsson, G., Kjeld, M., Bjarnason, I.  Effect of Pentavac and measles-mumps-rubella (MMR) vaccination on the intestine.  Gut.  2002 Dec;51(6):816-7.  http://www.ncbi.nlm.nih.gov/pubmed/12427783

Thompson, WW., Price, C., Goodson, B., Shay, DK., Benson, P., Hinrichsen, BL., Lewis, E., Eriksen, E., Ray, P., Marcy, SM., Dunn, J., Jackson, LA., Lieu, TA., Black, S., Stewart, G., Weintraub, ES., Davis, RL., DeStefano, F.,  Vaccine Data Link Safety Team.  Early thimerosal exposure and neuropsychological outcomes at 7 to 10 years.  New England Journal of Medicine.  2007 Sep 27;357(13):1281-92.  http://www.ncbi.nlm.nih.gov/pubmed/17898097

Uchiyama, T., Kurosawa, M., & Inaba, Y.  MMR-vaccine and regression in autism spectrum              disorders: negative results presented from Japan.  2007.  Journal of Autism and Developmental       Disorders, 37(2), 210-217.  http://www.ncbi.nlm.nih.gov/pubmed/16865547

Uno, Y., Uchiyama, T., Kurosawa, M., Aleksic, B., & Ozaki, N.  The combined measles, mumps, and rubella vaccines and the total number of vaccines are not associated with development of autism spectrum disorder:  first case–control study in Asia.  2012.  Vaccine, 30(28), 4292-4298. http://www.ncbi.nlm.nih.gov/pubmed/22521285

Verstraeten T., Davis, RL., DeStefano, F., Lieu, TA., Rhodes, PH., Black, SB., Shinefield, H., Chen RT. Safety of thimerosal-containing vaccines: a two-phased study of computerized health maintenance organization databases.   Pediatrics.   2003 Nov;112(5):1039-48. http://www.ncbi.nlm.nih.gov/pubmed/14595043

Whitehouse, AJ., Maybery, M., Wray, JA., Hickey, M.  No association between early gastrointestinal problems and autistic-like traits in the general population.  Developmental Medicine and Childhood Neurology.  2011.  May;53(5):457-62. doi: 10.1111/j.1469-8749.2011.03915.x. Epub 2011 Mar 21.  http://www.ncbi.nlm.nih.gov/pubmed/21418197

Weisser, K., Bauer, K., Volkers, P., Keller-Stanislawski, B.  Thimerosal and immunizations - evidence does not support the hypothesis of a potential relationship between neurodevelopmental disorders and thiomersal-containing vaccines.  2004. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz.  Dec;47(12):1165-74. http://www.ncbi.nlm.nih.gov/pubmed/15583887

MMR vaccine is not linked to Crohn’s disease or autismCommun Dis Rep CDR Weekly. 1998 Mar 27;8(13):113.  http://www.ncbi.nlm.nih.gov/pubmed/9592960

Sunday, September 1, 2013

Sharyl Attkisson and CBS Dehumanise Autists for Ratings

This past Friday Sharyl Attkisson, a journalist for CBS Network presented a "documentary" about a teenage autistic boy, Alex Spourdalakis who was pre-meditatively and brutally murdered by his mother and godmother.  If the murder of a special needs child by his own mother is horrific enough, Ms. Attkisson  and CBS add more insult to Alex's needless death by airing a carefully-staged faux documentary by none other than ex-doctor Andrew Wakefield.

Wakefield and his band of ghouls via his Autism Media Channel teamed up with Lisa Goes and Alex's mother Dorothy Spourdalakis creating the perfect storm of autism "biomed" crankery, narcissism and grotesque exploitation of a helpless teen autist for the shameless self-promotion that Wakefield has become so deft in.  Wakefield peddled this faux documentary along with other biomed stories to reality show execs earlier this year that featured Wakefield and his slimy crony gastroenterologist Arthur Krigsman that featured Wakefield as hero saving children from the horror that is autism.  I hope the sarcasm is noted.

It doesn't appear as though any of the represented networks were interested but Sharyl Attkisson and CBS didn't turn him down.  It is beyond disgusting that no one with editorial powers at CBS looked at this "documentary" and didn't even question its airing let alone question Ms. Attkisson's use of it with absolutely no journalistic ethics applied to the story.  Although since Sharyl Attkisson and CBS have been tools of anti-vaccine cranks that inhabit the cesspool known as Age of Autism, it shouldn't be surprising that they would think this is a nifty idea.

Alex Spourdalakis was a human being deserving of proper care and dignity, instead he was exploited to garner attention for the most execrable excuses for humans, one being his own mother.  Ms. Spourdalakis and her new-found mouthpieces Lisa Goes and Andrew Wakefield plead for help; she received several offers but only wanted an attorney.   There are so many inconsistencies in events leading up to Alex's death yet Ms. Attkisson and CBS exercised absolutely no due diligence verifying and fact-checking any facet of Wakefield's faux documentary. 

But that is not even the worst of Ms. Attkisson's and CBS's offences; they have given a platform to a group of people who routinely de-humanise autists and presented them as though they speak for the autism community.  These people are the same who say that children are better off dead than autistic.   Alex Spourdalakis was purposely shown nearly naked and restrained.  What kind of parent would not only allow such exploitation of her own child but stage it for ghouls like Wakefield to film and shop around for wider distribution?  Ms. Attkisson and CBS have promoted the dangerous idea that disabled people are expendable and their murderers are sympathetic characters to be pitied for their burdens and admired for their sacrifices.

CBS and Sharyl Attkisson owe Alex Spourdalakas and the autism community an enormous apology, a retraction of the story they aired and a real journalistic piece on the escalating victimisation of and violence perpetrated against disabled people.  They are the victims, not their murderers.  I urge you to contact CBS at the following to air your disgust (politely please) at their portrayal of the Spourdalakis case and the wider message that it's acceptable to exploit and murder special needs people:

CBS Chairman Jeffrey Fager, c/o CBS News, 524 West 57th Street, New York, N.Y. 10019

cbsaudiencenews@cbs.com

(hat tip to lilady who acquired the contact information and is spreading it wide and far)

Other bloggers who have weighed in:

http://leftbrainrightbrain.co.uk/2013/08/31/whitewashing-the-brutal-murder-of-alex-spourdalakis/

http://thepoxesblog.wordpress.com/2013/08/30/it-is-now-okay-to-kill-your-child/

http://www.skepticalraptor.com/skepticalraptorblog.php/vaccine-deniers-think-murder-alex-spourdalakis-acceptable/

http://paulacdurbinwestbyautisticblog.blogspot.com/

http://sciencebasedpharmacy.wordpress.com/2013/09/01/no-autism-doesnt-justify-murdering-your-child/

Added 2 September 2013:

http://scienceblogs.com/insolence/2013/09/02/sharyl-attkisson-and-cbs-news-an-epic-fail-in-reporting-on-the-murder-of-autistic-teen-alex-spourdalakis/

http://www.sciencebasedmedicine.org/sharyl-attkisson-promoting-wakefields-narrative-about-murder-alex-spourdalakis/

http://sciencebasedpharmacy.wordpress.com/2013/09/01/no-autism-doesnt-justify-murdering-your-child/

http://www.harpocratesspeaks.com/2013/09/cbs-sympathizes-with-murderers.html

Added 3 September 2013:

http://www.mediaite.com/tv/cbs-news-must-retract-report-excusing-mothers-murder-of-autistic-child/

http://lizditz.typepad.com/i_speak_of_dreams/2013/09/cbss-sharyl-attkisson-this-time-an-apologist-for-murder.html

Tuesday, July 9, 2013

The View of Jenny McCarthy

Jenny McCarthy, well known to those following anti-vaccine issues, is vying for a full-time position on ABC's The View in light of departing hosts.  Ms. McCarthy should not be given a platform that can potentially legitimise her and garner a wider audience to spread her anti-vaccine propaganda as Phil Plait writes about.  But even more insidious than her anti-vaccine activities, which she has tried to back away from in an attempt to re-vamp her failing image, is her role as organiser, spokesperson and sponsor of AutismOne.

AutismOne is the crank conference for all manner of quack "cures", "treatments" and "causes" (namely vaccines) for autism spectrum disorders.  The speakers and nostrums being touted at AutismOne are nothing short of child abuse of special needs children.  I have compiled a short list of the most notable "doctors" who Ms. McCarthy signs on to present at AutismOne year after year:

Andrew Wakefield has been named by TIME magazine, one of the great science frauds.  Dr. Wakefield has been struck of the UK's General Medical Council (analogous to the U.S.'s American Medical Association) for over 40 counts of unethical behaviours regarding his treatment of special needs children and others. Dr. Wakefield has also committed fraud regarding his findings that autism was caused by the MMR vaccine by fabricating data.  These studies were subsequently retracted.

Arthur Krigsman is a gastroenterologist who supports Andrew Wakefield's fraudulent science regarding MMR and autism.  He has been disciplined in numerous states for his own unethical behaviour.

Anjum Usman is being sued along with Dr. Dan Rossignol by a parent of an autistic child for unethical medical treatment of his child with chelation.  Dr. Rossignol didn't even examine the child yet prescribed chelation based upon bogus tests performed by Dr. Usman.  The father charges that his child has suffered harm as a result.  Illinois regulators are also seeking charges against Dr. Usman for, "“unprofessional, unethical and/or dishonorable conduct.”

Jeffrey Bradstreet has been lambasted by OAP Special Masters for his unethical and unsubstantiated treatment of autistic children with dangerous and unproven therapies including chelation, HBOT and potent prescription medications. Dr. Bradstreet also recommends exorcism for the "treatment" of autism.  Additionally, Dr. Bradstreet recommends stem cell therapy which is a potentially dangerous and completely untested therapy for autism.  Dr. Bradstreet even recommends unscrupulous, unregulated off-shore clinics.  Dr. Bradstreet also recommends "fecal transplants" for autistic children which is every bit as dreadful as it sounds.  Dr. Bradstreet tries to medicalise the procedure and provides instructions for laypeople, however parents' "biomed" discussion boards convey do-it-yourself "fecal transplants" based upon Dr. Bradstreet's advice that don't involve "donor" testing and amount to having a family member defecate in a bucket, mix it with some water, put the faecal slurry in a pastry bag and force the contents into the rectum of the autistic child.

Dr. Mark Geier and his son David Geier regularly present at AutismOne conferences.  Dr. Mark Geier's medical licence has been either suspended or revoked in all thirteen states he was licensed.   Additional charges against Dr. Geier are pendingDavid Geier has been charged with practising medicine without a license.  The reason that the Geier's have faced these charges is for using a powerful chemical-castration drug, Lupron in larger-than-adult-doses on autistic children and then chelating them.  This practise is extremely dangerous, cruel and has no medical basis whatsoever.  The Geier's also justify their use of Lupron to insurance companies by coding for "precocious puberty" even in teenage patients.  A fuller explanation of the Geier's gruesome experimentation on autistic children can be found here: http://en.wikipedia.org/wiki/Mark_Geier and here: http://articles.chicagotribune.com/2009-05-21/news/chi-autism-lupron-geiers-may21_1_vaccines-and-autism-mark-geier-autism-research

Mayer Eisenstein has also had actions brought against him for insurance fraud and several civil malpractice and fraud suits; this is just one of the doctors that work for Eisenstein.   Dr. Eisenstein proudly announces his anti-vaccine stance and is in business with the Geier's injecting autistic children with Lupron and chelating them.  Dr. Eisenstein is a regular fixture of AutismOne.

Kerri Rivera was a speaker at AutismOne this year and last year and presented her "cure" of autism with Miracle Mineral Solution (MMS) which is an industrial bleach.  Ms. Rivera is not a doctor and promotes the use of MMS as an enema, drink and bath to "cure" autism ( http://www.sciencebasedmedicine.org/index.php/bleaching-away-what-ails-you/ ).  Jenny McCarthy through AutismOne gave this woman a stage to disseminate this repulsive "treatment" to parents of autistic children who are desperate and vulnerable.  MMS has been banned in numerous countries and the FDA has issued a warning against it.

I urge you to write to ABC here and/or please sign the Change.org petition to let ABC know just who they are courting for one of their shows.   For the sake of brevity, you can link to this post to highlight Ms. McCarthy's dissemination of abusive "treatments" of special needs children.